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Krios G4 Cryo – Transmission Electron Microscopy (TEM)

The Krios G4 Cryo-TEM is a 300 kV cryo-transmission electron microscope engineered to enable 3D visualization of proteins and molecular machines at atomic level, their localization, and dynamics within the architecture of the biological cell.

Atomic resolution cryo-EM with enhanced productivity and compact design

The award-winning Thermo Scientific Krios G4 Cryo-Transmission Electron Microscope (Cryo-TEM) enables you to unravel life at the atomic level—easier, faster, and more reliably than ever before. The most compact TEM in its class, the Krios G4 Cryo-TEM consists of a highly stable 300 kV TEM platform and the industry-leading Autoloader (a cryogenic sample manipulation robot), making it ideally suited for automated applications such as cryo-electron tomography (cryo-ET), single-particle analysis (SPA), and micro-electron diffraction (MicroED).

The Thermo Scientific Falcon 4i Direct Electron Detector in 4 minutes

The Falcon 4i Direct Electron Detector is 30% faster while maintaining unsurpassed imaging quality with high detective quantum efficiency. Lossless data compression with Electron Event Representation and improved throughput increases productivity.

Krios Cryo-TEM Fringe-Free Imaging 

Acquire more images per sample area with fringe-free imaging (FFI), enhancing your daily data throughput.

Smart EPU Software for single particle analysis data collection

Smart EPU Software is an innovative, easy-to-use data acquisition solution or ecosystem for single particle analysis that focuses on automation and user guidance to increase throughput and deliver reproducible results.

Krios Cryo-TEM Aberration-Free Image Shift

Aberration-free image shift (AFIS) is an optical mode for faster data acquisition without comprising image quality. AFIS performs large beam shifts without off-axis coma and astigmatism.

  • Atomic resolution single particle analysis
  • Cellular cryo-tomography