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HistoCore NANOCUT R – Automated Rotary Microtome

Discover New Breakthroughs with an Enhanced Level of Precision and Versatility

When your microtomy involves diverse samples in order to discover new breakthroughs in your research projects, then NANOCUT R is the optimal solution for you. The new generation of microtomes from Leica Biosystems is built upon our 145+ year heritage of market-leading microtome design. From biomedical research to industrial applications, NANOCUT R can cut virtually anything you put in front of it.

  • Cut sections that can be prepared for analysis in light microscopy and electron microscopy – down to 250nm (0.25µm, semi-thin).
  • Preserve sample integrity when performing semi-thin sectioning with the Special Spindle and expanded Slow Speed Adjustment.
  • Precisely stop the sample in the object head’s optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.

Precise and Consistent Semi-Thin Sectioning

Avoid destruction of samples with the Special Spindle and expanded Slow Speed Adjustment capabilities which allow you to produce consistent semi-thin sections down to 250nm.

Tackle the Toughest Materials with a Wide Range of Accessories

Leverage a wide range of accessories available to the NANOCUT R, including holders for disposable steel and tungsten carbide blades, reusable knives, and a special holder for glass and diamond knives.

3D Reconstruction Stacking Technique

Precisely stop the sample in the object head’s optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.

Precision-Orientation System

Always get back to a 0-position home on the microtome, regardless of how you (or another tech) have changed the instrument’s orientation.

Force Balance System

Minimize the risk of injury to the operator or specimen by an unbalanced object head.


Type: Motorized
Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC
Nominal Frequency: 50/60 Hz
Maximum Power Consumption: 100 VA
Protection Class: I
Power Fuses: 2 x T3,15 AL, 250V
Pollution Degree: 2
Overvoltage Category: II
Maximum Heat Emission: 340 J/s
Operating Temperature Range: +18°C to +30°C
Temperature Range During Storage: +5°C to +50°C
Relative Humidity During Operation: 20% to Max. 80% Non-Condensing
Relative Humidity During Storage: 10% to Max. 85% Non-Condensing


Width (including handwheel): 415 mm
Depth (including waste tray): 620 mm
Height (without top tray): 295 mm
Weight (without accessories): Approx. 40 kg
Type: Separate control panel & in-housing integrated instrument control panel
Width: 119 mm
Depth: 193 mm
Height: 50 mm
Height (in inclined position): 81 mm
Weight (net): 0.6 kg


In Manual Sectioning Mode: 5 – 50 µm (in 5 µm increments); can be turned off
In Motorized Sectioning Mode: Speed-Dependent; can be turned off
Horizontal: ± 8°
Vertical: ± 8°
Range: 0.25 – 50 µm
Setting Values: 0.25 – 0.5 µm (in 0.25 µm increments)
0.5 – 5 µm (in 0.5 µm increments)
5 – 20 µm (in 1 µm increments)
20 – 50 µm (in 5 µm increments)
Range: 1 – 300 µm
Setting Values: 1 – 10 µm (in 1 µm increments)\

10 – 20 µm (in 2 µm increments)

20 – 50 µm (in 5 µm increments)

50 – 100 µm (in 10 µm increments)

100 – 300 µm (in 50 µm increments)