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VIA Freeze™ – Controlled-Rate Freezers

The VIA Freeze range of controlled-rate freezers are liquid nitrogen-free. They combine customizable freezing profiles, electronic control systems, and a conduction cooling method to optimize GMP-compliant cryopreservation.

The VIA Freeze range of controlled-rate freezers are liquid nitrogen-free. They combine customizable freezing profiles, electronic control systems, and a conduction cooling method to optimize GMP-compliant cryopreservation.

  • Controlled cooling. Maintain cell function and viability with therapy-specific freeze profiles and precise temperature control.
  • Consistent quality. Remove heat evenly from all samples thanks to conduction cooling. Standardize by reliably delivering profiles between networked units.
  • Clean room compatibility. Streamline manufacturing processes. Eliminate risks and infrastructure costs associated with liquid nitrogen.
  • Supports cGMP-compliant cryopreservation. Ready to integrate with cGMP process validation procedures. Controls designed to meet 21 CFR Part 11 regulations.
  • Versatility. Increase productivity without changing processes between VIA Freeze models. Options for 24–192 cryogenic vials, cryobags up to 250 mL, and straws.
  • Manufacturing automation. Incorporate freezing processes and profile run data into a complete digital batch record within Chronicle software. Monitor processes.

Choose your VIA Freeze model

Use the VIA Freeze Uno unit as a portable instrument or in a laboratory setting. Select VIA Freeze Duo for proof of concept experiments or low-volume production. Choose VIA Freeze Quad unit for production settings in a laboratory environment.

cGMP support

Each unit includes a calibration certificate. All models support web-based process monitoring. IQ and OQ documentation is available for each model.

Standardize and integrate cryopreservation processes

All VIA Freeze units integrate with Chronicle automation software, which can be purchased separately. Use Chronicle during process development to define optimized, therapy-specific controlled cooling profiles. Synchronize these profiles to all integrated VIA Freeze units to deliver approved cooling profiles across sites.

Add observer comments to the profile run data record within Chronicle. Combine these with cryopreservation eSOP data to develop a complete freeze process record as part of each sample’s electronic batch record. Access records and instrument alerts from the user interface or access remotely from any web browser.

Product overview and demo

Equipment services

OptiRun service solutions offer a comprehensive range of options that can be customized to your asset-management needs and desired outcomes. Learn more about service agreements and lifecycle support for your equipment.

Change Control Notifications

Our web-based Change Control Notification (CCN) service ensures that you are notified about changes that could potentially impact your product or process.

Capacity vials 48 × 2.0 mL standard cryovials
Cleaning Seamless sample area, no dirt traps, may be cleaned using standard wipes (Shield Medicare – Klerwipe™-CR)
Interface Secure ethernet interface for remote control in automated applications
Operating Temperature 5°C to 30°C
Portability Due to its low power requirements, can be run from an automotive 12 V power inverter or small portable generator
Power 250 VA
Sample plates 1
Size width 29.3 cm, depth 35.9 cm, height 44.9 cm
Software Onboard secure data logging and fully featured protocol editor
Supply 120–240 V AC, 50-60 Hz
Weight 14 kg (31 lb)
Capacity bags 250 mL baxter bag (with optional flat sample plate)
Capacity vials 192 × 2.0 mL standard cryovials
Cleaning Seamless sample area, no dirt traps, may be cleaned using standard wipes (Shield Medicare – Klerwipe™-CR)
Interface Secure ethernet interface for remote control in automated applications
Operating Temperature 5°C to 30°C
Power 650 VA
Sample plates 4
Size width 63.8 cm, depth 38.3 cm, height 61 cm
Software Onboard secure data logging and fully featured protocol editor
Supply 120–240 V AC, 50-60 Hz
Weight 64 kg (141 lb)
Capacity bags 125 mL baxter bag (with optional flat sample plate)
Capacity vials 96 × 2.0 mL standard cryovials
Cleaning Seamless sample area, no dirt traps, may be cleaned using standard wipes (Shield Medicare – Klerwipe™-CR)
Interface Secure ethernet interface for remote control in automated applications
Operating Temperature 5°C to 30°C
Power 350 VA
Sample plates 2
Size width 44.6 cm, depth 38.3 cm, height 61 cm
Software Onboard secure data logging and fully featured protocol editor
Supply 120–240 V AC, 50-60 Hz
Weight 40 kg (88 lb)