Overview
The NanoAssemblr™ Ignite system is a scalable, reproducible, and easy to use system for preclinical genomic medicine development. It formulates at the bench scale with volumes of up to 20 mL and flow rates of up to 20 mL/min.
The NanoAssemblr™ Ignite+ system builds on the features of the Ignite system with additional capabilities. It formulates up to 60 mL at up to 200 mL/min, enabling small-scale de-risking of large-scale systems and initiating process development activities using simple, low-volume workflows.
- Accelerated timelines – Simplified workflows and comprehensive technical support expedite drug development and data generation
- Reproducible – Automated and advanced NxGen™ mixing technology minimizes batch-to-batch and user variability to reproducibly generate homogenous particles
- Easy to use – Simple workflows and intuitive software allow users to be up and running quickly
- Minimized risk – The robust design of the system greatly reduces the chances of contamination and user errors, minimizing troubleshooting and downtime
- Controlled assembly – Precise control over fluid flow rates and ratios allows fine-tuning of the critical quality attributes (CQAs) including particle size to your specifications
- Scalable – The system enables modeling of clinically relevant parameters and processes at small volumes to predictably scale optimized formulations on the NanoAssemblr™ Blaze system and NanoAssemblr™ commercial formulation system
Scalable NxGen™ technology
The NxGen™ technology consists of a unique mixing architecture that includes toroidal structures within the flow path to ensure steady and consistent mixing conditions. This helps in the effective transfer of critical process parameters (CPPs) while scaling up by using our NanoAssemblr™ family of formulation systems, all of which are equipped with the same advanced NxGen™ technology. This minimizes process redevelopment and mitigates risk.
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